Human Genome Epidemiology (HuGE) Review Pooled Analysis and Meta-analysis of the Glutathione S-Transferase P1 Ile 105Val Polymorphism and Bladder Cancer: A HuGE-GSEC Review

نویسندگان

  • Eliane Kellen
  • Marjolein Hemelt
  • Karin Broberg
  • Klaus Golka
  • Vessela Nedelcheva Kristensen
  • Rayjean J. Hung
  • Giuseppe Matullo
  • Rama D. Mittal
  • Stefano Porru
  • Andrew Povey
  • Wolfgang A. Schulz
  • Jianhua Shen
  • Frank Buntinx
  • Maurice P. Zeegers
  • Emanuela Taioli
چکیده

1 Department of General Practice, Katholieke Universiteit Leuven, Comprehensive Cancer Institute Limburg, Limburg, Belgium. 2 Unit of Genetic Epidemiology, Department of Public Health and Epidemiology, University of Birmingham, Birmingham, United Kingdom. 3 Department of Occupational and Environmental Medicine andPsychiatricEpidemiology, LundUniversity, Lund,Sweden. 4 Institute for Occupational Physiology at the University of Dortmund, Dortmund, Germany. 5 Department of Genetics, Institute for Cancer Research, Norwegian Radium Hospital, Oslo, Norway. 6 Genetic Epidemiology Group, International Agency for Research on Cancer, Lyon, France. 7 Department of Genetics, Biology and Biochemistry, Faculty of Medicine and Surgery, University of Torino and ISI Foundation, Torino, Italy. 8 Department of Urology, Sanjay Gandhi Post Graduate Institute of Medical Sciences, Uttar Pradesh, India. 9 Institute of Occupational Health, University of Brescia, Brescia, Italy. 10 Centre for Occupational and Environmental Health, Medical School, University of Manchester, Manchester, United Kingdom. 11 Department of Urology, Heinrich Heine University, Duesseldorf, Germany. 12 Laboratory of Toxicology, Institute of Plant Physiology and Ecology, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai, People’s Republic of China. 13 Department of General Practice and Research Institute Caphri, Maastricht University, Maastricht, the Netherlands. 14 University of Pittsburgh Cancer Institute, University of Pittsburgh, Pittsburgh, PA.

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Pooled analysis and meta-analysis of the glutathione S-transferase P1 Ile 105Val polymorphism and bladder cancer: a HuGE-GSEC review.

The glutathione S-transferase P1 genotype (GSTP1) is involved in the inactivation of cigarette smoke carcinogens, and sequence variation in the gene may alter bladder cancer susceptibility. To examine the association between GSTP1Ile 105Val and bladder cancer, the authors undertook a meta- and pooled analysis. Summary crude and adjusted odds ratios and corresponding 95% confidence intervals wer...

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تاریخ انتشار 2007